Norfloxacin and N-Donor Mixed-Ligand Copper(II) Complexes: Synthesis, Albumin Interaction, and Anti-Trypanosoma cruzi Activity

Norfloxacin and N-Donor Mixed-Ligand Copper(II) Complexes: Synthesis, Albumin Interaction, and Anti-Trypanosoma cruzi Activity

Copper(II) complexes with the first-generation quinolone antibacterial agent norfloxacin containing a nitrogen donor heterocyclic ligand 2,2′-bipyridine (bipy) or 1,10-phenanthroline (phen) were prepared and characterized by IR, EPR spectra, molar conductivity, and elemental analyses. The experiment...

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Main Authors: Darliane A. Martins, Ligiane R. Gouvea, Gabriel S. Vignoli Muniz, Sonia R. W. Louro, Denise da Gama Jaen Batista, Maria de Nazaré C. Soeiro, Letícia R. Teixeira
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Bioinorganic Chemistry and Applications
Online Access:http://dx.doi.org/10.1155/2016/5027404
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