Comparisons of pharmacokinetics of glimepiride in combination with Ojeok-san versus glimepiride alone: an open-label, one-sequence, two-treatment controlled clinical study

Comparisons of pharmacokinetics of glimepiride in combination with Ojeok-san versus glimepiride alone: an open-label, one-sequence, two-treatment controlled clinical study

Abstract Glimepiride remains a cost-effective antidiabetic treatment despite its potential risks. However, its interaction with traditional medicines like Ojeok-san (OJS), a commonly used herbal medication, warrants investigation. This open-label, fixed-sequence, two-period, two-treatment crossover...

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Bibliographic Details
Main Authors: Jongyoon Kim, Minji Kwon, Sooyoung Lee, Jeein Noh, Wang-Seob Shim, Eunseo Song, Kyung-Tae Lee, Ji-Young Park, Sung-Vin Yim, Bo-Hyung Kim
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Glimepiride
Ojeok-san
Herb-Drug interaction
Pharmacokinetics
Online Access:https://doi.org/10.1038/s41598-025-09317-z
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https://doi.org/10.1038/s41598-025-09317-z

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