Deciphering the interaction between N-palmitoyl-D-glucosamine and the endocannabinoidome

Deciphering the interaction between N-palmitoyl-D-glucosamine and the endocannabinoidome

Abstract N-palmitoyl-D-glucosamine (PGA) belongs to the class of molecules known as Autacoid Local Injury Antagonism (ALIA)-amides, whose parent compound is N-palmitoyl-ethanolamine (PEA) an endocannabinoid-like mediator belonging to the expanded endocannabinoid system (the endocannabinoidome). The...

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Bibliographic Details
Main Authors: Aniello Schiano Moriello, Marco Allarà, Fabio Arturo Iannotti, Gabriele Marcolongo, Fabiana Piscitelli, Roberta Verde, Vincenzo Di Marzo, Stefania Petrosino
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
2-arachidonoyl-glycerol
ALIA-amides
Anandamide
Endocannabinoidome
N-palmitoyl-D-glucosamine
Palmitoylethanolamide
Online Access:https://doi.org/10.1038/s41598-025-07103-5
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https://doi.org/10.1038/s41598-025-07103-5

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