Exercise enhances cardiomyocyte mitochondrial homeostasis to alleviate left ventricular dysfunction in pressure overload induced remodelling

Exercise enhances cardiomyocyte mitochondrial homeostasis to alleviate left ventricular dysfunction in pressure overload induced remodelling

Abstract This study aims to explore how exercise enhances mitochondrial regulation and mitigates pathological cardiac hypertrophy. Rat groups were assigned as the control group (CN, n = 8), sham group (sham, n = 8), model group (SC, n = 16) and exercise group (SE, n = 20). A bioinformatics analysis...

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Bibliographic Details
Main Authors: Zhichao Ma, Yanling Cen, Weiwei Xun, Caiying Mou, Junwen Yu, Yarui Hu, Chen Liu, Jun Sun, Rui Bi, Yanli Qiu, Mingchao Ding, Li Jin
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Ndufb10
Exercise
Pathological cardiac hypertrophy
Mitochondrial dynamics
Cardiomyocyte
Online Access:https://doi.org/10.1038/s41598-025-95637-z
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https://doi.org/10.1038/s41598-025-95637-z

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