Development of a Mitochondrial Permeability Transition‐Driven Necrosis‐Related Prognostic Signature in Cervical Cancer: Integrating Bulk Transcriptomic and Single‐Cell Data

Development of a Mitochondrial Permeability Transition‐Driven Necrosis‐Related Prognostic Signature in Cervical Cancer: Integrating Bulk Transcriptomic and Single‐Cell Data

ABSTRACT Background Cervical cancer (CC) is a prevalent gynecological malignancy with notable heterogeneity. The role of mitochondrial permeability transition (MPT)‐driven necrosis, a form of cell death due to mitochondrial dysfunction, in CC progression and prognosis is poorly understood and repres...

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Bibliographic Details
Main Authors: Jiaojiao Niu, Sreenivasan Sasidharan
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Cancer Medicine
Subjects:
cell communication
cervical carcinoma
nomogram
prognostic genes
regulator network
Online Access:https://doi.org/10.1002/cam4.71094
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https://doi.org/10.1002/cam4.71094

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