High-quality draft genome and characterization of commercially potent probiotic strains

Lactobacillus acidophilus UBLA-34, L. paracasei UBLPC-35, L. plantarum UBLP-40, and L. reuteri UBLRU-87 were isolated from different varieties of fermented foods. To determine the probiotic safety at the strain level, the whole genome of the respective strains was sequenced, assembled, and character...

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Main Authors: Ayesha Sulthana, Suvarna G. Lakshmi, Ratna Sudha Madempudi
Format: Article
Language:English
Published: BioMed Central 2019-11-01
Series:Genomics & Informatics
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Online Access:http://genominfo.org/upload/pdf/gi-2019-17-4-e43.pdf
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author Ayesha Sulthana
Suvarna G. Lakshmi
Ratna Sudha Madempudi
author_facet Ayesha Sulthana
Suvarna G. Lakshmi
Ratna Sudha Madempudi
author_sort Ayesha Sulthana
collection DOAJ
description Lactobacillus acidophilus UBLA-34, L. paracasei UBLPC-35, L. plantarum UBLP-40, and L. reuteri UBLRU-87 were isolated from different varieties of fermented foods. To determine the probiotic safety at the strain level, the whole genome of the respective strains was sequenced, assembled, and characterized. Both the core-genome and pan-genome phylogeny showed that L. reuteri was closest to L. plantarum than to L. acidophilus, which was closest to L. paracasei. The genomic analysis of all the strains confirmed the absence of genes encoding putative virulence factors, antibiotic resistance, and the plasmids.
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institution Kabale University
issn 2234-0742
language English
publishDate 2019-11-01
publisher BioMed Central
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series Genomics & Informatics
spelling doaj-art-aee63634e3c04c37bd9a4e935f67ccbb2025-02-02T03:47:36ZengBioMed CentralGenomics & Informatics2234-07422019-11-0117410.5808/GI.2019.17.4.e43578High-quality draft genome and characterization of commercially potent probiotic strainsAyesha Sulthana0Suvarna G. Lakshmi1Ratna Sudha Madempudi2 Center for Research and Development, Unique Biotech Limited, Hyderabad 500 078, India Center for Research and Development, Unique Biotech Limited, Hyderabad 500 078, India Center for Research and Development, Unique Biotech Limited, Hyderabad 500 078, IndiaLactobacillus acidophilus UBLA-34, L. paracasei UBLPC-35, L. plantarum UBLP-40, and L. reuteri UBLRU-87 were isolated from different varieties of fermented foods. To determine the probiotic safety at the strain level, the whole genome of the respective strains was sequenced, assembled, and characterized. Both the core-genome and pan-genome phylogeny showed that L. reuteri was closest to L. plantarum than to L. acidophilus, which was closest to L. paracasei. The genomic analysis of all the strains confirmed the absence of genes encoding putative virulence factors, antibiotic resistance, and the plasmids.http://genominfo.org/upload/pdf/gi-2019-17-4-e43.pdfhigh-quality draft genomeprobioticssafety
spellingShingle Ayesha Sulthana
Suvarna G. Lakshmi
Ratna Sudha Madempudi
High-quality draft genome and characterization of commercially potent probiotic strains
Genomics & Informatics
high-quality draft genome
probiotics
safety
title High-quality draft genome and characterization of commercially potent probiotic strains
title_full High-quality draft genome and characterization of commercially potent probiotic strains
title_fullStr High-quality draft genome and characterization of commercially potent probiotic strains
title_full_unstemmed High-quality draft genome and characterization of commercially potent probiotic strains
title_short High-quality draft genome and characterization of commercially potent probiotic strains
title_sort high quality draft genome and characterization of commercially potent probiotic strains
topic high-quality draft genome
probiotics
safety
url http://genominfo.org/upload/pdf/gi-2019-17-4-e43.pdf
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AT ratnasudhamadempudi highqualitydraftgenomeandcharacterizationofcommerciallypotentprobioticstrains