High-quality draft genome and characterization of commercially potent probiotic strains
Lactobacillus acidophilus UBLA-34, L. paracasei UBLPC-35, L. plantarum UBLP-40, and L. reuteri UBLRU-87 were isolated from different varieties of fermented foods. To determine the probiotic safety at the strain level, the whole genome of the respective strains was sequenced, assembled, and character...
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| Format: | Article |
| Language: | English |
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BioMed Central
2019-11-01
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| Series: | Genomics & Informatics |
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| Online Access: | http://genominfo.org/upload/pdf/gi-2019-17-4-e43.pdf |
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| author | Ayesha Sulthana Suvarna G. Lakshmi Ratna Sudha Madempudi |
| author_facet | Ayesha Sulthana Suvarna G. Lakshmi Ratna Sudha Madempudi |
| author_sort | Ayesha Sulthana |
| collection | DOAJ |
| description | Lactobacillus acidophilus UBLA-34, L. paracasei UBLPC-35, L. plantarum UBLP-40, and L. reuteri UBLRU-87 were isolated from different varieties of fermented foods. To determine the probiotic safety at the strain level, the whole genome of the respective strains was sequenced, assembled, and characterized. Both the core-genome and pan-genome phylogeny showed that L. reuteri was closest to L. plantarum than to L. acidophilus, which was closest to L. paracasei. The genomic analysis of all the strains confirmed the absence of genes encoding putative virulence factors, antibiotic resistance, and the plasmids. |
| format | Article |
| id | doaj-art-aee63634e3c04c37bd9a4e935f67ccbb |
| institution | Kabale University |
| issn | 2234-0742 |
| language | English |
| publishDate | 2019-11-01 |
| publisher | BioMed Central |
| record_format | Article |
| series | Genomics & Informatics |
| spelling | doaj-art-aee63634e3c04c37bd9a4e935f67ccbb2025-02-02T03:47:36ZengBioMed CentralGenomics & Informatics2234-07422019-11-0117410.5808/GI.2019.17.4.e43578High-quality draft genome and characterization of commercially potent probiotic strainsAyesha Sulthana0Suvarna G. Lakshmi1Ratna Sudha Madempudi2 Center for Research and Development, Unique Biotech Limited, Hyderabad 500 078, India Center for Research and Development, Unique Biotech Limited, Hyderabad 500 078, India Center for Research and Development, Unique Biotech Limited, Hyderabad 500 078, IndiaLactobacillus acidophilus UBLA-34, L. paracasei UBLPC-35, L. plantarum UBLP-40, and L. reuteri UBLRU-87 were isolated from different varieties of fermented foods. To determine the probiotic safety at the strain level, the whole genome of the respective strains was sequenced, assembled, and characterized. Both the core-genome and pan-genome phylogeny showed that L. reuteri was closest to L. plantarum than to L. acidophilus, which was closest to L. paracasei. The genomic analysis of all the strains confirmed the absence of genes encoding putative virulence factors, antibiotic resistance, and the plasmids.http://genominfo.org/upload/pdf/gi-2019-17-4-e43.pdfhigh-quality draft genomeprobioticssafety |
| spellingShingle | Ayesha Sulthana Suvarna G. Lakshmi Ratna Sudha Madempudi High-quality draft genome and characterization of commercially potent probiotic strains Genomics & Informatics high-quality draft genome probiotics safety |
| title | High-quality draft genome and characterization of commercially potent probiotic strains |
| title_full | High-quality draft genome and characterization of commercially potent probiotic strains |
| title_fullStr | High-quality draft genome and characterization of commercially potent probiotic strains |
| title_full_unstemmed | High-quality draft genome and characterization of commercially potent probiotic strains |
| title_short | High-quality draft genome and characterization of commercially potent probiotic strains |
| title_sort | high quality draft genome and characterization of commercially potent probiotic strains |
| topic | high-quality draft genome probiotics safety |
| url | http://genominfo.org/upload/pdf/gi-2019-17-4-e43.pdf |
| work_keys_str_mv | AT ayeshasulthana highqualitydraftgenomeandcharacterizationofcommerciallypotentprobioticstrains AT suvarnaglakshmi highqualitydraftgenomeandcharacterizationofcommerciallypotentprobioticstrains AT ratnasudhamadempudi highqualitydraftgenomeandcharacterizationofcommerciallypotentprobioticstrains |