Modeling the metabolic response of A2780 ovarian cancer cells to gold-based cytotoxic drugs

Abstract Gold compounds are a promising class of experimental anticancer metallodrugs. Unlike platinum-based drugs, their antiproliferative effects are thought to result mainly from modulation of cancer cell metabolism rather than direct interaction with DNA. Previous NMR studies have shown that fou...

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Bibliographic Details
Main Authors: Walter Vieri, Veronica Ghini, Paola Turano, Lara Massai, Luigi Messori, Marco Fondi
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-025-00535-9
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