Automated inference of disease mechanisms in patient-hiPSC-derived neuronal networks

Abstract Human induced pluripotent stem cells (hiPSCs)-derived neuronal networks on multi-electrode arrays (MEAs) are a powerful tool for studying neurological disorders. The electric activity patterns of these networks differ between healthy and patient-derived neurons, reflecting underlying pathol...

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Bibliographic Details
Main Authors: Nina Doorn, Michel J. A. M. van Putten, Monica Frega
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08209-2
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