SIRT2-dependent CPT1A deacetylation in macrophages inhibits periodontitis

SIRT2-dependent CPT1A deacetylation in macrophages inhibits periodontitis

IntroductionPeriodontitis is intricately related to systemic disorders and exerts a negative impact on quality of life. Recent studies have suggested a potential association between periodontitis and fatty acid oxidation (FAO), a key metabolic process involved in energy production and cellular funct...

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Bibliographic Details
Main Authors: Yixuan Jiang, Xiu Yao, Zhizhong Jiang, Xiaomeng Liu, Boyuan Sun, Zhengyu Guan, Lin Zhou, Hongjiao Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Pharmacology
Subjects:
CPT1A
SIRT2
periodontitis
macrophage
deacetylation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1574141/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1574141/full

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