419 The MEK1/2 inhibitor ATR-002 has dual anti-inflammatory and antibacterial effects during S. aureus infection

Objectives/Goals: Novel therapeutics to control Staphylococcus aureus (S. aureus) infections are needed for people with cystic fibrosis (CF, PwCF). In this study, our objective is to determine if the pharmacologic MEK1/2 inhibitor compound ATR-002 can restrict the growth of S. aureus clinical isolat...

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Bibliographic Details
Main Authors: Eryn Zuiker, Mithu De, Gregory Serpa, Matthew E. Long
Format: Article
Language:English
Published: Cambridge University Press 2025-04-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866124010276/type/journal_article
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