Degree and Rate of Growth Discordance in Dichorionic Twins Conceived by In Vitro Fertilization
Objective. Our objective was to estimate degree and rate of discordant growth and its impact on perinatal outcome in dichorionic twin pregnancies conceived by in vitro fertilization (IVF) compared to those conceived spontaneously. Study Design. Growth discordance was defined as 90th percentiles for...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Obstetrics and Gynecology International |
| Online Access: | http://dx.doi.org/10.1155/2014/543728 |
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| author | Amira S. Egic Donka V. Mojovic Zagorka M. Milovanovic Aleksandar B. Jurisic Ljubomir P. Srbinovic Suzana P. Krsmanovic Natasa T. Karadzov-Orlic |
| author_facet | Amira S. Egic Donka V. Mojovic Zagorka M. Milovanovic Aleksandar B. Jurisic Ljubomir P. Srbinovic Suzana P. Krsmanovic Natasa T. Karadzov-Orlic |
| author_sort | Amira S. Egic |
| collection | DOAJ |
| description | Objective. Our objective was to estimate degree and rate of discordant growth and its impact on perinatal outcome in dichorionic twin pregnancies conceived by in vitro fertilization (IVF) compared to those conceived spontaneously. Study Design. Growth discordance was defined as 90th percentiles for the study population. Adverse perinatal outcome was defined as 5-minute Apgar score <7 and/or admission to neonatal intensive care unit. Results. In the total study population of dichorionic twins (176 conceived by IVF and 215 spontaneously), 30% discordant growth represented the 90th percentile. After adjusting for gestational age, discordant twins conceived by IVF or spontaneously were at higher risk for adverse perinatal outcome (hazard ratio 4.4; 95% CI 2.4–8.3, P<0.0001; hazard ratio 2.5; 95% CI 1.5–4.4, P=0.001, resp.). Similar rates of 5-minute Apgar score <7, admission to neonatal intensive care unit, and delivery <34 weeks were found between discordant twins conceived by IVF and those conceived spontaneously. Conclusion. Dichorionic twins conceived by IVF are at similar risk for the rate and degree of discordant growth and adverse perinatal outcome compared to dichorionic twins conceived spontaneously. |
| format | Article |
| id | doaj-art-ae91d559776145a3a3d10e1836fc0c20 |
| institution | Kabale University |
| issn | 1687-9589 1687-9597 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Obstetrics and Gynecology International |
| spelling | doaj-art-ae91d559776145a3a3d10e1836fc0c202025-02-03T07:25:05ZengWileyObstetrics and Gynecology International1687-95891687-95972014-01-01201410.1155/2014/543728543728Degree and Rate of Growth Discordance in Dichorionic Twins Conceived by In Vitro FertilizationAmira S. Egic0Donka V. Mojovic1Zagorka M. Milovanovic2Aleksandar B. Jurisic3Ljubomir P. Srbinovic4Suzana P. Krsmanovic5Natasa T. Karadzov-Orlic6High-Risk Pregnancy Department, Obstetric and Gynecology Clinic “Narodni Front”, University of Belgrade, Street Kraljice Natalije 62, 11000 Belgrade, SerbiaHigh-Risk Pregnancy Department, Obstetric and Gynecology Clinic “Narodni Front”, University of Belgrade, Street Kraljice Natalije 62, 11000 Belgrade, SerbiaHigh-Risk Pregnancy Department, Obstetric and Gynecology Clinic “Narodni Front”, University of Belgrade, Street Kraljice Natalije 62, 11000 Belgrade, SerbiaHigh-Risk Pregnancy Department, Obstetric and Gynecology Clinic “Narodni Front”, University of Belgrade, Street Kraljice Natalije 62, 11000 Belgrade, SerbiaHigh-Risk Pregnancy Department, Obstetric and Gynecology Clinic “Narodni Front”, University of Belgrade, Street Kraljice Natalije 62, 11000 Belgrade, SerbiaHigh-Risk Pregnancy Department, Obstetric and Gynecology Clinic “Narodni Front”, University of Belgrade, Street Kraljice Natalije 62, 11000 Belgrade, SerbiaHigh-Risk Pregnancy Department, Obstetric and Gynecology Clinic “Narodni Front”, University of Belgrade, Street Kraljice Natalije 62, 11000 Belgrade, SerbiaObjective. Our objective was to estimate degree and rate of discordant growth and its impact on perinatal outcome in dichorionic twin pregnancies conceived by in vitro fertilization (IVF) compared to those conceived spontaneously. Study Design. Growth discordance was defined as 90th percentiles for the study population. Adverse perinatal outcome was defined as 5-minute Apgar score <7 and/or admission to neonatal intensive care unit. Results. In the total study population of dichorionic twins (176 conceived by IVF and 215 spontaneously), 30% discordant growth represented the 90th percentile. After adjusting for gestational age, discordant twins conceived by IVF or spontaneously were at higher risk for adverse perinatal outcome (hazard ratio 4.4; 95% CI 2.4–8.3, P<0.0001; hazard ratio 2.5; 95% CI 1.5–4.4, P=0.001, resp.). Similar rates of 5-minute Apgar score <7, admission to neonatal intensive care unit, and delivery <34 weeks were found between discordant twins conceived by IVF and those conceived spontaneously. Conclusion. Dichorionic twins conceived by IVF are at similar risk for the rate and degree of discordant growth and adverse perinatal outcome compared to dichorionic twins conceived spontaneously.http://dx.doi.org/10.1155/2014/543728 |
| spellingShingle | Amira S. Egic Donka V. Mojovic Zagorka M. Milovanovic Aleksandar B. Jurisic Ljubomir P. Srbinovic Suzana P. Krsmanovic Natasa T. Karadzov-Orlic Degree and Rate of Growth Discordance in Dichorionic Twins Conceived by In Vitro Fertilization Obstetrics and Gynecology International |
| title | Degree and Rate of Growth Discordance in Dichorionic Twins Conceived by In Vitro Fertilization |
| title_full | Degree and Rate of Growth Discordance in Dichorionic Twins Conceived by In Vitro Fertilization |
| title_fullStr | Degree and Rate of Growth Discordance in Dichorionic Twins Conceived by In Vitro Fertilization |
| title_full_unstemmed | Degree and Rate of Growth Discordance in Dichorionic Twins Conceived by In Vitro Fertilization |
| title_short | Degree and Rate of Growth Discordance in Dichorionic Twins Conceived by In Vitro Fertilization |
| title_sort | degree and rate of growth discordance in dichorionic twins conceived by in vitro fertilization |
| url | http://dx.doi.org/10.1155/2014/543728 |
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