The frequencies of CYP2C19*2, *3, and *17 alleles and their impact on the clinical efficacy of doubled maintenance dose of clopidogrel in Syrian patients with coronary artery disease

The frequencies of CYP2C19*2, *3, and *17 alleles and their impact on the clinical efficacy of doubled maintenance dose of clopidogrel in Syrian patients with coronary artery disease

Abstract Background Genetic variations in the CYP2C19 gene, which encodes the major enzyme responsible for activating clopidogrel, may influence response to Clopidogrel antiplatelet therapy. This study aimed to assess the prevalence of CYP2C19 variants in Syrian patients with coronary artery disease...

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Bibliographic Details
Main Authors: Nour Haj Saleh, Lama A. Youssef
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Cardiovascular Disorders
Subjects:
Clopidogrel
Doubled maintenance dose
CYP2C19
Genotyping
CYP2C19*2
CYP2C19*3
Online Access:https://doi.org/10.1186/s12872-025-04768-8
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https://doi.org/10.1186/s12872-025-04768-8

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