Malignant epithelial cell marker–driven risk signature enables precise stratification in esophageal cancer

BackgroundEsophageal squamous cell carcinoma (ESCC) is a highly heterogeneous malignancy. Traditional clinical staging systems have limited value in prognostic evaluation and treatment guidance, often failing to capture the profound impact of intratumoral diversity on patient outcomes. Single-cell R...

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Bibliographic Details
Main Authors: Hao Zhang, Shizhao Cheng, Yijun Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1610991/full
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