Exploring the Causal Relationship Between the Plasma Levels of MMP1 (Matrix Metalloproteinase‐1), MMP3, MMP7, MMP10, and MMP12 and Intervertebral Disc Degeneration: Mendelian Randomization

Exploring the Causal Relationship Between the Plasma Levels of MMP1 (Matrix Metalloproteinase‐1), MMP3, MMP7, MMP10, and MMP12 and Intervertebral Disc Degeneration: Mendelian Randomization

ABSTRACT Background Several matrix metalloproteinases (MMPs) have been reported to be associated with intervertebral disc degeneration (IDD) in several previous studies. However, the causal relationship between MMPs and IDD remains unclear. In this study, Mendelian randomization (MR) was used to ana...

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Bibliographic Details
Main Authors: Lin Sun, Kai‐Qing Yan, Qi Zhang, Ji Ma, Bo Shi, Xi‐Yuan Yang, Li‐Jun Li
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:JOR Spine
Subjects:
intervertebral disc degeneration
matrix metalloproteinase‐3
matrix metalloproteinases
Mendelian randomization
Online Access:https://doi.org/10.1002/jsp2.70034
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https://doi.org/10.1002/jsp2.70034

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