Photon-counting in dual-contrast-enhanced computed tomography: a proof-of-concept quantitative biomechanical assessment of articular cartilage

Photon-counting in dual-contrast-enhanced computed tomography: a proof-of-concept quantitative biomechanical assessment of articular cartilage

Abstract This proof-of-concept study explores quantitative imaging of articular cartilage using photon-counting detector computed tomography (PCD-CT) with a dual-contrast agent approach, comparing it to clinical dual-energy CT (DECT). The diffusion of cationic iodinated CA4 + and non-ionic gadoliniu...

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Bibliographic Details
Main Authors: Petri Paakkari, Satu I. Inkinen, Ali Mohammadi, Miika T. Nieminen, Anisha Joenathan, Mark W. Grinstaff, Juha Töyräs, Janne T. A. Mäkelä, Juuso T. J. Honkanen
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Photon-counting detector
Contrast-enhanced computed tomography
Dual-energy computed tomography
Biomechanical indentation
Articular cartilage
Osteoarthritis
Online Access:https://doi.org/10.1038/s41598-024-78237-1
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https://doi.org/10.1038/s41598-024-78237-1

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