Predictors of pathological complete response after total neoadjuvant treatment using short course radiotherapy for locally advanced rectal cancer

Predictors of pathological complete response after total neoadjuvant treatment using short course radiotherapy for locally advanced rectal cancer

Abstract Background Total neoadjuvant treatment (TNT) has become a standard treatment approach for locally advanced rectal cancer (LARC). Patients achieving pathological complete response (pCR) following TNT have better outcomes (overall survival, relapse free survival). However, not all patients tr...

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Main Authors: Haythem Yacoub, Yosr Zenzri, Dhouha Cherif, Hajer Ben Mansour, Najla Attia, Cyrine Mokrani, Khadija Ben Zid, Feryel Letaief, Nadia Maamouri, Amel Mezlini
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Gastroenterology
Subjects:
Pathological complete response
Locally advanced rectal cancer
Total neoadjuvant treatment
Radiotherapy
Chemotherapy
Online Access:https://doi.org/10.1186/s12876-025-03709-1
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https://doi.org/10.1186/s12876-025-03709-1

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