Recombinant Factor C as an In Vitro Assay for the Residual Pathogenicity Evaluation of Veterinary Autogenous Vaccines

Recombinant Factor C as an In Vitro Assay for the Residual Pathogenicity Evaluation of Veterinary Autogenous Vaccines

Background: Veterinary autogenous vaccines, similar to all injectable pharmaceutical products, must be tested to assess endotoxin concentrations. The Limulus Amebocyte Lysate Test (LAL test) is widely used in in vitro quality control assays for endotoxin detection, although it presents some ethical...

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Bibliographic Details
Main Authors: Antonella Di Paolo, Rosario Liberti, Lucia Anzalone, Claudia Colabella, Andrea Felici, Giulio Severi, Monica Cagiola
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Veterinary Sciences
Subjects:
bacterial endotoxin testing
recombinant factor C
LAL test
veterinary autogenous vaccine
Online Access:https://www.mdpi.com/2306-7381/11/12/673
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