Sesamol Inhibits Aβ1-42-Induced Ferroptosis by Regulating the SLC7A11/GPX4/ACSL4 Axis in PC12 Cells

The purpose of this study was to investigate the effect and mechanism of sesamol (SE) on amyloid-β (Aβ) induced ferroptosis in pheochromocytoma (PC12) cells. A PC12 cell of ferroptosis induced by erastin, RSL-3 or Aβ1-42 was established and evaluated by the CCK-8 method, and the effective protective...

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Bibliographic Details
Main Author: ZHAO Peijun, WANG Tianlin, XIE Shanshan, SONG Lianjun, HUANG Xianqing, LI Tiange
Format: Article
Language:English
Published: China Food Publishing Company 2025-05-01
Series:Shipin Kexue
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Online Access:https://www.spkx.net.cn/fileup/1002-6630/PDF/2025-46-10-015.pdf
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