Engineered antibody-mediated broad-spectrum suppression of human arboviruses in the Aedes aegypti vector

Abstract Mosquito-borne orthoflaviviruses such as dengue and Zika viruses, and alphaviruses such as chikungunya viruses continue to pose global health threats, necessitating innovative vector control strategies. Small antibodies (sAb) such as single-chain variable fragments (scFv) and single-domain...

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Bibliographic Details
Main Authors: Shengzhang Dong, Mihra Tavadia, Qiran Amy Dong, George Dimopoulos
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08133-5
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