Synergistic effects of Pandanus fascicularis extracts and azithromycin: in vitro and in silico antimicrobial investigation against MDR clinical strains

Synergistic effects of Pandanus fascicularis extracts and azithromycin: in vitro and in silico antimicrobial investigation against MDR clinical strains

BackgroundAntibiotic-resistant bacteria are becoming a significant global concern. To combat the spread of resistance or reverse multidrug resistance, developing novel antimicrobials and/or resistance modulators is essential. This study aimed to evaluate the synergistic effects of the methanolic ext...

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Main Authors: Mst. Hajera Khatun, Md Rashedul Islam, Shikha Khatun, Amro Ahmed Zalah, Md. Hadisur Rahman Rony, Mst. Munira Khatun, Emad Essa A. Wasili, Jaytirmoy Barmon, Saad Ahmed Sami, Abdulrahman Hadi Masmali, Ishtiaq Qadri
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Antibiotics
Subjects:
multidrug-resistant bacteria
synergistic effect
clinical strains
antioxidant activity
Pandanus fascicularis
natural products
Online Access:https://www.frontiersin.org/articles/10.3389/frabi.2025.1552382/full
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https://www.frontiersin.org/articles/10.3389/frabi.2025.1552382/full

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