Fluorescence Polarization-Based High-Throughput Screening Assay for Inhibitors Targeting Cathepsin L

Cathepsin L (CTSL), a lysosomal cysteine protease belonging to the papain-like protease family, is primarily involved in intracellular protein degradation, antigen processing, and extracellular matrix remodeling. It plays critical roles in pathological conditions, including cancer metastasis, neurod...

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Bibliographic Details
Main Authors: Keyu Guo, Baoqing You, Wenwen Zhou, Yan Li, Zhen Wang, Jing Zhang, Shuyi Si
Format: Article
Language:English
Published: Bio-protocol LLC 2025-07-01
Series:Bio-Protocol
Online Access:https://bio-protocol.org/en/bpdetail?id=5400&type=0
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