Plasmodium falciparum malaria runs a more severe course in splenectomized patients at comparable levels of parasitemia: a retrospective matched case-control study

Abstract Background The spleen plays a vital role in combating Plasmodium infections, particularly during the erythrocytic stage of the infection. Asplenia may notably affect disease progression and parasite clearance dynamics. More insight is needed as to whether asplenic malaria patients - beyond...

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Bibliographic Details
Main Authors: Maria I. Otto, Klaske J. Vliegenthart-Jongbloed, Jaap J. van Hellemond, Perry JJ van Genderen
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Tropical Diseases, Travel Medicine and Vaccines
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Online Access:https://doi.org/10.1186/s40794-025-00255-2
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