Insights into the transcriptomic heterogeneity of brain endothelial cells in normal aging and Alzheimer’s disease

Drug development for Alzheimer’s disease is extremely challenging, as demonstrated by the repeated failures of amyloid-β-targeted therapeutics and the controversies surrounding the amyloid-β cascade hypothesis. More recently, advances in the development of Lecanemab, an anti-amyloid-β monoclonal ant...

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Bibliographic Details
Main Authors: Qian Yue, Shang Li, Chon Lok Lei, Huaibin Wan, Zaijun Zhang, Maggie Pui Man Hoi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2026-02-01
Series:Neural Regeneration Research
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Online Access:https://journals.lww.com/10.4103/NRR.NRR-D-24-00695
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