Toll-like receptor 9 (TLR9) expression correlates with cell of origin and predicts clinical outcome in diffuse large B-cell lymphoma

Toll-like receptor 9 (TLR9) expression correlates with cell of origin and predicts clinical outcome in diffuse large B-cell lymphoma

Abstract Background Biological insights beyond the cell-of-origin (COO) classification can support clinical management in diffuse large B-cell lymphoma (DLBCL). We investigated if Toll-like receptor 9 (TLR9) expression could serve as a prognostic marker in DLBCL. Method TLR9 gene expression was anal...

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Main Authors: Sulaf Abd Own, Ioanna Xagoraris, Konstantina Stathopoulou, Björn E. Wahlin, Weicheng Ren, Mehran Ghaderi, Qiang Pan-Hammarström, Birgitta Sander, Karin E. Smedby, Georgios Rassidakis
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Cancer
Subjects:
TLR9
Biomarker
Prognosis
DLBCL
Online Access:https://doi.org/10.1186/s12885-025-14359-7
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https://doi.org/10.1186/s12885-025-14359-7

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