Neuroprotective role of morin hydrate on 3-nitropropionic acid-elicited huntington's disease: in vivo investigation of RIPK1/RIPK3/MLKL necroptosis signaling pathway

Abstract Background Huntington’s disease (HD) is a rare dominantly inheritable autosomal neurodegenerative disease with unclear pathophysiological pathways. In neurodegenerative disorders, including HD, necroptosis plays a significant role in neuronal death. Morin hydrate (MH), a natural bioactive f...

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Bibliographic Details
Main Authors: Eman M. Elbaz, Rabab H. Sayed, Amany A. Abdelkader, Atef Tadros Fahim
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Molecular Medicine
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Online Access:https://doi.org/10.1186/s10020-025-01172-y
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