Plumbagin targets the GLUT1/MMP-2 axis to inhibit oral squamous cell carcinoma progression

Plumbagin targets the GLUT1/MMP-2 axis to inhibit oral squamous cell carcinoma progression

Abstract Aim This study aimed to investigate the clinicopathological characteristics and prognostic value of GLUT1 in oral squamous cell carcinoma (OSCC) and the effect of plumbagin (PLB) on inhibiting OSCC invasion and metastasis through the GLUT1/Matrix Metalloproteinase 2 (MMP2) axis pathway. Mat...

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Bibliographic Details
Main Authors: Fei He, Weiqi Wang, Sadam Ahmed Elayah, Linyang Xie, Ming Yu, Yuxin Gong, Hao Cui, Xiang Liang, Junbo Tu, Ying Han, Sijia Na
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Cancer Cell International
Subjects:
Plumbagin
Oral squamous cell carcinoma
Glucose transporter 1
Matrix metalloproteinase 2
Invasion and metastasis
Online Access:https://doi.org/10.1186/s12935-025-03915-7
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https://doi.org/10.1186/s12935-025-03915-7

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