Hypermethylation of Hif3a and Ifltd1 is associated with atrial remodeling in pressure-overload murine model

Hypermethylation of Hif3a and Ifltd1 is associated with atrial remodeling in pressure-overload murine model

Abstract Atrial remodeling is a major pathophysiological mechanism of atrial fibrillation (AF). Atrial remodeling progresses with aging and background diseases, including hypertension, heart failure, and AF itself. However, its mechanism of action and reversibility have not been completely elucidate...

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Bibliographic Details
Main Authors: Keiko Abe, Tetsuo Sasano, Yurie Soejima, Haruhisa Fukayama, Shigeru Maeda, Tetsushi Furukawa
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Atrial fibrillation
Atrial remodeling
Reverse remodeling
Methylation
Hif3a
Ifltd1
Online Access:https://doi.org/10.1038/s41598-025-85382-8
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