Volume Management in the Critically Ill Patient with Acute Kidney Injury

Acute kidney injury (AKI) frequently occurs in the setting of critical illness and its management poses a challenge for the intensivist. Optimal management of volume status is critical in the setting of AKI in the ICU patient. The use of urine sodium, the fractional excretion of sodium (FeNa), and t...

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Main Authors: Mary Labib, Raeesa Khalid, Akram Khan, Supriya Khan
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Critical Care Research and Practice
Online Access:http://dx.doi.org/10.1155/2013/792830
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author Mary Labib
Raeesa Khalid
Akram Khan
Supriya Khan
author_facet Mary Labib
Raeesa Khalid
Akram Khan
Supriya Khan
author_sort Mary Labib
collection DOAJ
description Acute kidney injury (AKI) frequently occurs in the setting of critical illness and its management poses a challenge for the intensivist. Optimal management of volume status is critical in the setting of AKI in the ICU patient. The use of urine sodium, the fractional excretion of sodium (FeNa), and the fractional excretion of urea (FeUrea) are common clinical tools used to help guide fluid management especially further volume expansion but should be used in the context of the patient’s overall clinical scenario as they are not completely sensitive or specific for the finding of volume depletion and can be misleading. In the case of oliguric or anuric AKI, diuretics are often utilized to increase the urine output although current evidence suggests that they are best reserved for the treatment of volume overload and hyperkalemia in patients who are likely to respond to them. Management of volume overload in ICU patients with AKI is especially important as volume overload has several negative effects on organ function and overall morbidity and mortality.
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spelling doaj-art-adbd3701f5a34c9aae6d5f94967c6b682025-02-03T01:22:54ZengWileyCritical Care Research and Practice2090-13052090-13132013-01-01201310.1155/2013/792830792830Volume Management in the Critically Ill Patient with Acute Kidney InjuryMary Labib0Raeesa Khalid1Akram Khan2Supriya Khan3Nephrology & Hypertension, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, CH12R, Portland, OR 97239-3098, USAPulmonary & Critical Care Medicine, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, UHN67, Portland, OR 97239-3098, USAPulmonary & Critical Care Medicine, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, UHN67, Portland, OR 97239-3098, USANephrology & Hypertension, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, CH12R, Portland, OR 97239-3098, USAAcute kidney injury (AKI) frequently occurs in the setting of critical illness and its management poses a challenge for the intensivist. Optimal management of volume status is critical in the setting of AKI in the ICU patient. The use of urine sodium, the fractional excretion of sodium (FeNa), and the fractional excretion of urea (FeUrea) are common clinical tools used to help guide fluid management especially further volume expansion but should be used in the context of the patient’s overall clinical scenario as they are not completely sensitive or specific for the finding of volume depletion and can be misleading. In the case of oliguric or anuric AKI, diuretics are often utilized to increase the urine output although current evidence suggests that they are best reserved for the treatment of volume overload and hyperkalemia in patients who are likely to respond to them. Management of volume overload in ICU patients with AKI is especially important as volume overload has several negative effects on organ function and overall morbidity and mortality.http://dx.doi.org/10.1155/2013/792830
spellingShingle Mary Labib
Raeesa Khalid
Akram Khan
Supriya Khan
Volume Management in the Critically Ill Patient with Acute Kidney Injury
Critical Care Research and Practice
title Volume Management in the Critically Ill Patient with Acute Kidney Injury
title_full Volume Management in the Critically Ill Patient with Acute Kidney Injury
title_fullStr Volume Management in the Critically Ill Patient with Acute Kidney Injury
title_full_unstemmed Volume Management in the Critically Ill Patient with Acute Kidney Injury
title_short Volume Management in the Critically Ill Patient with Acute Kidney Injury
title_sort volume management in the critically ill patient with acute kidney injury
url http://dx.doi.org/10.1155/2013/792830
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AT supriyakhan volumemanagementinthecriticallyillpatientwithacutekidneyinjury