ERO1α regulates curcumin-induced autophagy via PI3K/AKT pathway

ERO1α regulates curcumin-induced autophagy via PI3K/AKT pathway

Objective: Through comprehensive analysis of cisplatin-resistant HeLa cervical cancer cells, we reveal that curcumin exerts potent anti-cancer effects by modulating autophagic processes, and further identify Endoplasmic reticulum oxidoreductase 1-alpha (ERO1α) as a key regulator mediating this biolo...

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Bibliographic Details
Main Authors: Dandan Huang, Bolorchimeg Baldandorj, Erdenezaya Odkhuu, Egshiglen Amartuvshin, Damdindorj Boldbaatar, Hairong Guo, Adilsaikhan Mendjargal
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Cancer Treatment and Research Communications
Subjects:
Curcumin
Cervical cancer
ERO1α
PI3K/AKT pathway
Autophagy
Online Access:http://www.sciencedirect.com/science/article/pii/S2468294225000930
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