Survival and pathological response in pancreatic ductal adenocarcinoma after preoperative therapy with PD-1 blockade plus chemoradiotherapy followed by surgical resection

Survival and pathological response in pancreatic ductal adenocarcinoma after preoperative therapy with PD-1 blockade plus chemoradiotherapy followed by surgical resection

Background Neoadjuvant PD-1 blockade plus chemoradiotherapy has resulted in improved clinical response in pancreatic ductal adenocarcinoma (PDAC); however, the effects on pathological response (PR) and survival remain unknown. This study was to identify the survival and PR of patients with PDAC unde...

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Main Authors: Elyar Abaydulla, Qi Li, Jialing Li, Defu Hu, Song Zhang, Shanshan Shen, Jian He, Aimei Li, Min Tang, Jun Chen, Huizi Sha, Liang Mao, Lei Wang, Juan Du, Yudong Qiu, Hao Cheng
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Annals of Medicine
Subjects:
Neoadjuvant therapy
chemoradiotherapy
immunotherapy
pancreatic ductal adenocarcinoma
complete pathological response
survival
Online Access:https://www.tandfonline.com/doi/10.1080/07853890.2025.2541314
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https://www.tandfonline.com/doi/10.1080/07853890.2025.2541314

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