Radiochemical and biological assessments of a PSMA-I&S cold kit for fast and inexpensive 99mTc-labeling for SPECT imaging and radioguided surgery in prostate cancer

Radiochemical and biological assessments of a PSMA-I&S cold kit for fast and inexpensive 99mTc-labeling for SPECT imaging and radioguided surgery in prostate cancer

The expression of prostate-specific membrane antigen (PSMA) is upregulated in prostate cancer (PCa) cells and PSMA-ligands have been radiolabeled and used as radiopharmaceuticals for targeted radionuclide therapy (TRT), single photon emission computed tomography (SPECT) or positron emission tomograp...

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Bibliographic Details
Main Authors: Leonardo Lima Fuscaldi, Danielle Vieira Sobral, Ana Claudia Ranucci Durante, Fernanda Ferreira Mendonça, Ana Cláudia Camargo Miranda, Carla Salgueiro, Silvia Gomez de Castiglia, Lilian Yuri Itaya Yamaga, Marcelo Livorsi da Cunha, Luciana Malavolta, Marycel Figols de Barboza, Jorge Mejia
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Chemistry
Subjects:
PSMA-I&S
technetium-99m
cold kits for radiopharmaceuticals
SPECT imaging
radioguided surgery
prostate cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2023.1271176/full
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https://www.frontiersin.org/articles/10.3389/fchem.2023.1271176/full

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