Piezo1 selectively enhances TGF-β1-induced IgA class switching by B cells

Abstract Piezo1 is a mechanosensitive cationic channel that regulates Ca2+ influx, gene transcription, and cell migration. Recent studies suggest that Piezo1 affects regulatory T cells differentiation and is critical in B cell responses to membrane-presented antigens. However, the role of Piezo1 in...

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Bibliographic Details
Main Authors: Yoonji Jung, Younghwan Han, Jaeku Kang, Seong-Lan Yu, Seok-Rae Park
Format: Article
Language:English
Published: Springer 2025-06-01
Series:Cellular and Molecular Life Sciences
Subjects:
Online Access:https://doi.org/10.1007/s00018-025-05789-4
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