Causal relationships between immune cell traits and HER2 subtypes in breast cancer: a Mendelian randomization study

Abstract Background Breast cancer can be classified based on HER2 status into HER2-positive (HER2+) and HER2-negative (HER2-) subtypes, which differ significantly in pathogenesis, prognosis, and treatment response. Immune cells are critical components of the tumor microenvironment, influencing breas...

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Bibliographic Details
Main Authors: Fenfen Gu, Chuling Hu, Chao Li
Format: Article
Language:English
Published: Springer 2025-08-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-025-03358-6
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