Low-pass nanopore sequencing for measurement of global methylation levels in plants

Low-pass nanopore sequencing for measurement of global methylation levels in plants

Abstract Nanopore sequencing enables detection of DNA methylation at the same time as identification of canonical sequence. A recent study validated low-pass nanopore sequencing to accurately estimate global methylation levels in vertebrates with sequencing coverage as low as 0.01x. We investigated...

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Bibliographic Details
Main Authors: Yusmiati Liau, Annabel Whibley, Amy M. Hill, Bhanupratap R. Vanga, Meeghan Pither-Joyce, Elena Hilario, Sarah Bailey, Susan J. Thomson, Darrell Lizamore
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Genomics
Subjects:
Nanopore methylation sequencing
Skimseq
Plant
Vitis vinifera
Online Access:https://doi.org/10.1186/s12864-024-11145-w
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https://doi.org/10.1186/s12864-024-11145-w

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