Insights into rapid screening and molecular mechanism of novel Rosa roxburghii seeds pancreatic lipase/cholesterol esterase inhibitory peptides: a combined in silico and in vitro perspective

Insights into rapid screening and molecular mechanism of novel Rosa roxburghii seeds pancreatic lipase/cholesterol esterase inhibitory peptides: a combined in silico and in vitro perspective

Rosa roxburghii seeds are by-products of R. roxburghii processing, and their protein hydrolysates (RTSPHs) were found to possess a variety of biological activities. This study aimed to rapidly identify pancreatic lipase (PL) and cholesterol esterase (CE) inhibitory peptides in RTSPHs and to elucidat...

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Bibliographic Details
Main Authors: Hao Yin, Jiangxiong Zhu, Yu Zhong, Danfeng Wang, Yun Deng, Yongli Jiang, Linnan Yang, Lutao Gao
Format: Article
Language:English
Published: Tsinghua University Press 2025-07-01
Series:Food Science and Human Wellness
Subjects:
bioactive peptide
enzyme inhibiting
virtual screening
molecular docking
inhibition kinetics
Online Access:https://www.sciopen.com/article/10.26599/FSHW.2024.9250163
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https://www.sciopen.com/article/10.26599/FSHW.2024.9250163

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