Diastereoselective Cyclization of a Glycyl-alanine Azomethine to an Imidazolidinone: Determination of the Product Configuration by X-Ray Analysis

Glycyl-(5')-alanine-esters 1 and 2 can be condensed to the corresponding 4-oxo-imidazolidin-3-yl-propionates 3 and 4, respectively. The diastereomers 3a and 4a are formed preferentially and the configuration was found to be u by single crystal X-ray diffraction of 4a. The crystal structure sho...

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Bibliographic Details
Main Authors: Martin Egli, Robin Polt, Dieter Seebach
Format: Article
Language:deu
Published: Swiss Chemical Society 1989-02-01
Series:CHIMIA
Online Access:https://www.chimia.ch/chimia/article/view/9882
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