Characterization of a Potential Therapeutic Anti-Canine PD-1 Single Domain Antibody Produced in Yeast

A single domain antibody (SDAb) targeting canine PD-1 was developed as a potential immunotherapeutic for canine cancer. An alpaca was immunized with canine PD-1 protein, and a phage-display library was constructed using mRNA isolated from peripheral lymphocytes. Screening of the library yielded mult...

Full description

Saved in:
Bibliographic Details
Main Authors: Kartikeya Vijayasimha, Andrew J. Annalora, Dan V. Mourich, Carl E. Ruby, Brian P. Dolan, Laura Crowell, Vu Ha Minh Le, Maureen K. Larson, Shay Bracha, Christopher K. Cebra
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Veterinary Sciences
Subjects:
Online Access:https://www.mdpi.com/2306-7381/12/7/649
Tags: Add Tag
No Tags, Be the first to tag this record!