Investigating potential drug targets for the treatment of glioblastoma: a Mendelian randomization study

Abstract Glioblastoma (GBM), one of the most aggressive brain tumors, has a 5-year survival rate of less than 5%. Current standard therapies, including surgery, radiotherapy, and temozolomide (TMZ) chemotherapy, are limited by drug resistance and the blood–brain barrier. Integrating expression quant...

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Bibliographic Details
Main Authors: Hongwei Zhang, Zixuan Wang, Xiaolong Qiao, Jiaxing Wu, Chuandong Cheng
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Cancer
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Online Access:https://doi.org/10.1186/s12885-025-13979-3
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