Smart biomimetic “nano-med-fireman” blocking inflammation and lactate metabolism crosstalk for normalized spatiotemporal photo-immunotherapy

Smart biomimetic “nano-med-fireman” blocking inflammation and lactate metabolism crosstalk for normalized spatiotemporal photo-immunotherapy

The immense complexity and interconnectedness of inflammation and metabolism in the primary tumor ecosystem and pre-metastatic niches (PMN) present an enormous challenge for developing advanced nano-medicines for cancer immunotherapy. Herein, an intelligent tumor- and PMN-tropic bioactive “nano-med-...

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Bibliographic Details
Main Authors: Honglin Huang, Ningxi Li, Li Zeng, Qianyi Zeng, Ziman Yang, Jinyang Shen, Xiaodan Wei, Hong Yang, Dengfeng Wang, Yiyao Liu, Chunhui Wu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-09-01
Series:Bioactive Materials
Subjects:
Inflammation modulation
Cytokine neutralization
Lactate metabolism regulation
Pre-metastatic niche reprogramming
Photothermal immunotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X25001987
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http://www.sciencedirect.com/science/article/pii/S2452199X25001987

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