Characterization of the genome editing with miniature DNA nucleases TnpB and IscB in Escherichia coli strains
Abstract DNA endonucleases TnpB and IscB are emerging candidates for combating drug-resistant bacteria, particularly Escherichia coli, due to their specificity in targeting DNA and smaller size. However, the genome-editing of TnpB/IscB in E. coli remains unclear. This study characterized the genome...
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| Main Authors: | Hongjie Tang, Jie Gao, Hengyi Wang, Mingjun Sun, Suyi Zhang, Chuan Song, Qi Li |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-02-01
|
| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-025-07521-1 |
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