Connective tissue disorder and high risk pregnancy: a case series with personalised external aortic root support (PEARS)

Connective tissue disorder and high risk pregnancy: a case series with personalised external aortic root support (PEARS)

Abstract Aortopathy including Marfan (MFS) and Loeys-Dietz syndrome (LDS) poses a high risk of aortic dissection, particularly during pregnancy and the puerperium. Current preventive measures of aortic root dilatation include medical therapy and prophylactic aortic root replacement. The Personalised...

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Main Authors: Claudia Montanaro, Polona Kacar, Giulia Iannaccone, John Pepper, Gurleen Wander, Christoph A. Nienaber, Andreas Hoschtitzky, Mario Petrou, Hannah Douglas, Mark R. Johnson, Roshni R. Patel, Isma Rafiq, Michael A. Gatzoulis
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61241-y
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https://doi.org/10.1038/s41467-025-61241-y

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