High-fat and low-fiber diet elevates the gut resistome: a comparative metagenomic study

Abstract Antimicrobial resistance (AMR) is a global health challenge. The gut microbiome, a major reservoir for AMR, is influenced by dietary habits. However, the specific impact of dietary patterns on gut resistome remains poorly understood. This study aimed to assess the effects of high-fat/low-fi...

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Main Authors: Yingbo Shen, Da Sun, Kun Chen, Junyao Jiang, Dongyan Shao, Lu Yang, Chengtao Sun, Dejun Liu, Yuebin Ke, Congming Wu, Timothy R. Walsh, Jianzhong Shen, Ziquan Lv, Yang Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:npj Biofilms and Microbiomes
Online Access:https://doi.org/10.1038/s41522-025-00799-3
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