Treatment-resistant depression and intranasal esketamine: Spanish consensus on theoretical aspects

Treatment-resistant depression and intranasal esketamine: Spanish consensus on theoretical aspects

IntroductionDepression is a highly prevalent disease that severely impacts the life of patients. Inadequate response to at least two antidepressants despite adequacy of treatment and adherence is known as treatment-resistant depression (TRD), which entails a higher social and economic burden than no...

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Main Authors: Fernando Mora, Jose Antoni Ramos-Quiroga, Enrique Baca-García, José Manuel Crespo, Luis Gutiérrez-Rojas, Aránzazu Madrazo, Lucía Pérez Costillas, Pilar A. Saiz, Vicente Tordera, Eduard Vieta
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Psychiatry
Subjects:
intranasal esketamine
definition
therapeutic inertia
Spain
consensus
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1623659/full
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https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1623659/full

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