PoreWalker: a novel tool for the identification and characterization of channels in transmembrane proteins from their three-dimensional structure.

Transmembrane channel proteins play pivotal roles in maintaining the homeostasis and responsiveness of cells and the cross-membrane electrochemical gradient by mediating the transport of ions and molecules through biological membranes. Therefore, computational methods which, given a set of 3D coordi...

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Bibliographic Details
Main Authors: Marialuisa Pellegrini-Calace, Tim Maiwald, Janet M Thornton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000440&type=printable
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