Apremilast treatment of immune-mediated inflammatory skin diseases: a narrative review

Novel therapeutic approaches on molecular pathways are being developed to treat inflammatory and autoimmune cutaneous dermatoses. Apremilast is an orally administered small-molecule phosphodiesterase 4 (PDE4) inhibitor that upregulates intracellular cyclic 3′,5′-adenosine monophosphate (cAMP) levels...

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Bibliographic Details
Main Authors: Xiaoqian Liang, Jiecheng Zheng, Xueyi Huang, Min Tan, Jia Liao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1633426/full
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