Derivation and validation of a non-invasive optoacoustic imaging biomarker for detection of patients with intermittent claudication

Abstract Background Peripheral arterial disease (PAD) affects more than 200 million people worldwide, with symptoms ranging from none to severe. Despite these different diagnostic options, patients with unclear leg pain remain challenging to diagnose. The primary objective of this study was to evalu...

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Main Authors: Milenko Caranovic, Julius Kempf, Yi Li, Adrian P. Regensburger, Josefine S. Günther, Anna P. Träger, Werner Lang, Alexander Meyer, Alexandra L. Wagner, Joachim Woelfle, Roman Raming, Lars-Philip Paulus, Adrian Buehler, Wolfgang Uter, Michael Uder, Christian-Alexander Behrendt, Markus F. Neurath, Maximilian J. Waldner, Ferdinand Knieling, Ulrich Rother
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-025-00801-1
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