Immune dysfunction during S. aureus biofilm-associated implant infections: opportunities for novel therapeutic strategies

Abstract Staphylococcus aureus is a common cause of biofilm infections, particularly on implanted medical devices. Biofilms are heterogeneous bacterial communities contained in a self-produced matrix that are poorly cleared by the immune system. This review discusses mechanisms employed by the biofi...

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Bibliographic Details
Main Authors: Nichole D. Brandquist, Tammy Kielian
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Biofilms and Microbiomes
Online Access:https://doi.org/10.1038/s41522-025-00782-y
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