Identification of key modules and hub genes for sepsis-induced myopathy using weighted gene co-expression network analysis

Identification of key modules and hub genes for sepsis-induced myopathy using weighted gene co-expression network analysis

BackgroundSepsis-induced myopathy (SIM) is a severe complication of sepsis, leading to significant muscle dysfunction and increased mortality. The molecular mechanisms underlying SIM remain poorly understood, necessitating comprehensive studies to identify potential therapeutic targets. This study a...

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Bibliographic Details
Main Authors: Siming Lin, Kexin Cai, Ai Chen, Weibin Wu, Guili Lian, Shaodan Feng, Zhihong Lin, Liangdi Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Genetics
Subjects:
sepsis-induced myopathy
skeletal muscle
hub genes
biomarkers
bioinformatics
WGCNA
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2025.1607575/full
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https://www.frontiersin.org/articles/10.3389/fgene.2025.1607575/full

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