Pharmacokinetics and Tissue Distribution of Enavogliflozin in Mice Using a Validated Liquid Chromatography–Tandem Mass Spectrometry Method

Pharmacokinetics and Tissue Distribution of Enavogliflozin in Mice Using a Validated Liquid Chromatography–Tandem Mass Spectrometry Method

Enavogliflozin, a sodium–glucose cotransporter 2 inhibitor, was approved in 2022 by the Korean Ministry of Food and Drug Safety as a therapeutic agent for type 2 diabetes mellitus and has been investigated for expanded therapeutic efficacy in diabetic retinopathy and cardioprotection. In this study,...

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Bibliographic Details
Main Authors: Minyeong Pang, Jihoon Lee, Min-Koo Choi, Im-Sook Song
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Applied Sciences
Subjects:
enavogliflozin
SGLT2 inhibitor
LC-MS/MS
analytical validation
pharmacokinetics
tissue distribution
Online Access:https://www.mdpi.com/2076-3417/15/3/1445
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