Association of Hepatitis B Virus Polymerase/Surface Gene Overlap Mutations Developed in Nucleos(t)id Analogue Treatments of Chronic Hepatitis B with Hepatocellular Carcinoma

Association of Hepatitis B Virus Polymerase/Surface Gene Overlap Mutations Developed in Nucleos(t)id Analogue Treatments of Chronic Hepatitis B with Hepatocellular Carcinoma

Aim: Nucleos(t)id analogs (NA) used in hepatitis B virus (HBV) treatment may cause rtA181T and sW172* mutations. sW172* increases progression to hepatocellular carcinoma (HCC). This study aimed to reveal the rtA181T/sW172* mutation in HCC patients on the background of chronic hepatitis B (CHB) to de...

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Bibliographic Details
Main Authors: Yeşim Saliha Gürbüz, Seda Erem Basmaz, Murat Sayan, Sadettin Hülagü
Format: Article
Language:English
Published: Duzce University 2025-04-01
Series:Düzce Tıp Fakültesi Dergisi
Subjects:
hepatocellular carcinoma
hepatitis b virus
drug resistance
nucleos(t)id analog
hepatosellüler karsinom
hepatit b virüsü
ilaç direnci
nükleoz(t)id analoğu
Online Access:https://dergipark.org.tr/en/download/article-file/4116310
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